Syrian state media says security forces have imposed a cordon around the area and are investigating.
At least six people have been killed and more than 20 injured when an explosion struck a mosque in Syria’s Homs province.
The attack targeted the Imam Ali bin Abi Talib Mosque in the Wadi al-Dahab neighbourhood of Homs shortly after Friday prayers, the Syrian Arab News Agency (SANA) reported.
Footage verified by Al Jazeera showed people fleeing the mosque in panic, placing some victims on stretchers and carrying others, wrapped in cloaks, to ambulances.
The blast appeared to have taken place in the corner of the mosque’s main prayer hall, leaving a small crater in the wall and scorching the surrounding area, with prayer carpets ripped and strewn with debris, books and fragments scattered across the floor.
Local officials told the Reuters news agency the blast may have been caused by a suicide bomber or explosives placed there.
State media said security forces had imposed a cordon around the area and were investigating.
Ayman Oghanna, Al Jazeera’s correspondent in Aleppo, noted that Homs is home to a diverse population of Alawites, Christians and Sunni Muslims. He said the attack targeted an Alawite mosque, warning it could “inflame sectarian tensions” across the country.
He said no group had claimed responsibility for the strike, but noted a recent surge in ISIL (ISIS) activity in Syria. He added that government forces had carried out an operation near Aleppo, arresting three alleged ISIL members.
Last week the United States bombed ISIL positions in Syria in retaliation for the killings of two US soldiers and a civilian interpreter. Damascus also joined a global anti-ISIL alliance in November, vowing to crush the remaining elements of the group.
Friday’s attack underscores the country’s fragile security situation, as the new authorities in Damascus struggle to assert control.