‘My blood test today showed a PSA of 12.9 ng/ml. Is there any medicine my urologist can give me that will lower it?’

What does a PSA or Prostate-Specific Antigen level of 12.9 ng/mL indicate? As a Quora user’s question caught our attention, we decided to pose the same to a doctor: “My blood test today showed a PSA of 12.9. Is there any medicine that my urologist can give me that will lower it?” According to Dr Amit Saraf, director, internal medicine, Jupiter Hospital, Thane, PSA is an antigenic enzyme released by the prostate in men. A PSA level of 12.9 ng/ml is clearly above the normal range and should not be ignored.

“However, it’s important to understand that PSA is not a disease but a marker produced by the prostate gland. Medicines are not prescribed to bring down the PSA number without first identifying why it is elevated,” said Dr Saraf.

A high PSA can result from several conditions. Dr Saraf said that these include benign prostate enlargement, prostatitis or infection, recent urinary procedures, ejaculation shortly before the test, or prostate cancer. “Even a urinary infection can temporarily raise PSA levels. This is why one single PSA value should never be viewed alone,” said Dr Saraf.

Here’s what you should consider (Photo: Freepik)

Yes, but only in specific situations, affirmed Dr Saraf. “If the PSA is high due to infection or inflammation, antibiotics or anti-inflammatory medicines may be prescribed, and PSA often decreases once the condition resolves. Certain drugs for prostate enlargement, like 5-alpha reductase inhibitors, can lower PSA over time, but these are not diagnostic tools and should not be started blindly. Importantly, medicines should never be used to mask PSA levels before a proper evaluation.”

Your doctor may recommend a repeat PSA test, often after a few weeks, under controlled conditions. “A digital rectal examination, urine tests, or imaging, such as a prostate MRI, may be suggested. The trend of PSA—whether it is rising quickly is often more informative than a single reading,” said Dr Saraf.

The Quora query (Photo: Quora)

While a PSA of 12.9 ng/ml does raise concern, it does not automatically mean cancer, noted Dr Saraf. “The risk depends on age, PSA trend, prostate exam findings, family history, and imaging results. Early detection, when necessary, allows for very effective treatment options,” said Dr Saraf.

Avoid panic, self-medication, or conclusions based on internet searches. “Also, don’t delay evaluation, hoping that the number will settle on its own. Timely assessment makes a real difference.”

DISCLAIMER: This article is based on information from the public domain and/or the experts we spoke to. Always consult your health practitioner before starting any routine.